The FDA approved Avastin in 2008 even though the clinical studies did not show any benefit. There were some studies showing that the drug slowed tumour growth. The studies were obviously done by the drug company. The medical advisory panel recommended that Avastin should not be approved because it was not effective. The FDA approved it anyway. Therefore thousands of women suffered from side effects of Avastin, without getting any benefit. Their insurance companies spent $100,000 a year for each patient. The insurance companies raised premiums for everybody to cover their costs.
Several clinical studies and two more advisory committee meetings were conducted to answer the question if Avastin was safe and effective. Finally the FDA saw the light of day and withdrew its approval of Avastin for breast cancer.
Meanwhile Genentech made 6 billion dollars every year, selling a drug that does more harm than good. Welcome to miracles of modern medicine!